All totals are unofficially until certified by Pike County Clerk Melissa Kempke.
| Republican Ticket | Democratic Ticket | ||
| U.S. Senator | U.S. Senator | ||
| Tony Monetti | 255 | Carla (Coffee) Wright | 147 |
| Austin Petersen | 205 | Angelica Earl | 47 |
| Josh Hawley | 1001 | Leonard Joseph Steinman II | 94 |
| Fred Ryman | 48 | John Hogan | 107 |
| Christina Smith | 105 | Travis Gonzalez | 41 |
| Kristi Nichols | 124 | David Faust | 118 |
| Bradley Krembs | 21 | Claire McCaskill | 1229 |
| Ken Patterson | 67 | ||
| Brian G. Hagg | 34 | U.S. Representative 6th District | |
| Courtland Sykes | 31 | Winston Apple | 306 |
| Peter Pfeifer | 71 | Henry Robert Martin | 894 |
| Ed Andres | 282 | ||
| State Auditor | |||
| Kevin M. Roach | 363 | Pike County Collector of Revenue | |
| David Wasinger | 756 | Tara Morrison Eskew | 1172 |
| Paul Curtman | 211 | Rhonda Niemeyer | 755 |
| Saundra McDowell | 522 | ||
| Senate 18t District | |||
| Lindell F. Shumake | 396 | ||
| Craig Redmon | 438 | ||
| Cindy O'Laughlin | 941 | ||
| Nate Walker | 197 | ||
| Circuit Judge | |||
| Patrick S. Flynn | 1228 | ||
| Chris Kunza Mennemeyer | 534 | ||
| Lee Elliott | 321 | ||
| Green Party Ticket | Propositions | ||
| U.S. Senator | Prop A – Right to Work | ||
| Jo Crain | 1 | Yes | 1142 |
| Jerome Bauer | 2 | No | 3146 |
| Prop 911 | |||
| Yes | 3426 | ||
| No | 832 | ||
| City of Clarkville Use Tax | |||
| Yes | 57 | ||
| No | 52 | ||
| City of Eolia Use Tax | |||
| Yes | 70 | ||
| No | 74 | ||