| 8/28 | Louisiana | 22 | @ | North Callaway | 74 | ||
| 9/4 | Louisiana | 15 | vs | Montgomery County | 40 | ||
| 9/11 | Louisiana | 12 | vs | South Callaway | 55 | ||
| 9/18 | Louisiana | 6 | @ | Clopton/Elsberry | 27 | ||
| 9/25 | Louisiana | 35 | vs | Van-Far/Community R-VI | 28 | ||
| 10/2 | Louisiana | 34 | @ | Missouri Military Academy | 47 | ||
| 10/9 | Louisiana | @ | Bowling Green | Cancelled | |||
| 10/16 | Louisiana | 20 | vs | Wright City | 55 | ||
| 10/23 | Louisiana | 28 | @ | Mark Twain | 6 | ||
| Districts – Class 1 District 2 | |||||||
| 10/23 | (6) Louisiana | vs | (3) Principia | FFT | Opening Round | ||
| 11/6 | (6) Louisiana | 24 | (2) Mark Twain | 36 | Semi-Final | ||